Expedite 8905/8909:
Based on micropumps these synthesizer can process 2 parallel syntheses from 0,05 up to 15 µmol.
Standard Configuration is 5 (8905) or 9 (8909) Amidite Positions with 20 or 40 ml.
One Position for Iodine- and one for Thio Oxidizer (only 8909) up to 450 ml
One Position for internal Wash up to 450 ml
Two Positions for Capping reagents up to 450 ml
One Activator position up to 450 ml
Acetonitrile Wash up to 4 L
Deblock up to 4 L
On line Trityl monitoring and waste separation
PC Based Software available (Windows 95, 98Se )
With the new XP Software it is possible to run Expedites with a Windows XP Computer
ABI 392 / Abi 394:
The classic models. DNA / RNA Synthesizer with 2 or 4 columns and either 4 or 8 Amidite positions (up to 60 ml).
One position for Iodine
One position for Ammonia/AMA for cleavage on the machine or for Thioation up to 450 ml
Two Positions for Capping reagents up to 450 ml
One Activator position up to 450 ml
Acetonitrile Wash up to 4 L
Deblock up to 4L
Dichlormethane up to 4L
Usually with on line trityl monitoring based on conductivity.
Very low dead volumes, very economical with the low volume cycles,
Up to more than 100 bases.
Easy Cycle editing with Oligonet Software via Mac Computers
ABI 3900 HT Synthesizer:
Rotor Based DNA or RNA Synthesizer for 4 banks with max. 12 columns each.
Typical scales 40 -1000 nmol with cpg or polystyrol
2 x 4 Standard Amidite positions and 2 x 3 special amidites (up to 60 ml)
One position for Iodine
Two Positions for Capping reagents up to 450 ml
One Activator position up to 450 ml
Acetonitrile Wash up to 2 x 4 L
Deblock up to 4L
One synthesis cycle with 48 columns in parallel can be achieved in 8 min.
Easy cycle editing with Spread Sheet Editors
Controlling via Windows NT/2000 or XP Software
Dr. Oligo™ 96 / 192
High Throughput Oligo Synthesizers that synthesize oligos in a 96 well plate format. Dr. Oligo™ synthesizes anywhere from 1 to 96 oligos at a time in lengths from 1 base to 150 bases.
Individual Bottle Sizes for the amidites from 30 ml to 450 ml
Reagent Bottle Sizes usually 1 L
Two Cap Positions
One Oxidizer and optional auxiliary oxidizer
Acetonitril and Deblock Bottles usually 4 L
Scale from 20 to 1000 nmol; on filter plates, cpg frits or ABI 3900 columns
One synthesis cycle with 192 columns in parallel can be achieved in 8 min.
Very high coupling yields compared with other plate synthesizers.
On line Trityl Monitoring available
Highly flexible Software
Peptide Synthesizer ABI 431/433